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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f8247b362104da347166f04b8c3dc3d7f8556d8d37323056a286a59ead474c0' 
  AND token = '9QEFhx3J7cghBSrPjp7F6g1HxFcTAnKIi1QD3tY2zyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}