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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4d3bee0022df81eb8d2fc095d097549d1c7d3e11e27f984a1157d3651ef0a2' 
  AND token = 'CDQgiIpmHVMus4q1wYJeN79o2Fv5Gxpse45LNVxx2pA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}