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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b80836b4316d6a36415d087bef7f6208c04025f55d98a023492ed0cbc48e997d' 
  AND token = '+DzG31bCDwu+HYlh/G+ltpO2HcIy04u2DN9OfSBWf+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}