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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2ad08d09a17a0bf7cf6a630586ca4f0bcc09d893f8fe7dba3908c54145cb04' 
  AND token = 'sIwUD52NI9/rmEL1KTlyYLsNtCkAAZmiiYGJivirUNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}