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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64211412e524ff7fa13862f6029687b418770a561a49bca33a40955ca10dbc3c' 
  AND token = 'Gqq1rCe4O3i+EM/OztXvqZqnNGRYG3EkhVP1GXt1/I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}