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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ca8f665c453af657c1da40e0f1bb56f98340741de72ffb7e42d17922ddbc57' 
  AND token = 'EHmyjIVWzqqIS0YT9zHMoIsAVZamLL5qarqnDg6Z05A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}