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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb7c4b1b67b0f88b7fd16c61590ebbe5003052a3334bc4e369ade21afa008f20' 
  AND token = 'nYl1lp0qBb8/RP6BOiX9iSaqdG1CUTQIDoYRJvz0kQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}