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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c37ce5bbe7cb5deace4416511c8dfd29e9d627026094f129756b59776cf38662' 
  AND token = '/Jq1U74nh32Q1YuthWjq7zMcG5rtERpJgyT8nUEWKUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}