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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6603641779d29325f100e87ee04dcfe356aa6adfea793d590b618f62a5b090b8' 
  AND token = 'XawYKiBLf+2esx6j2qMwUkssjYRcC2p7tTrCutgQl/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}