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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc49d07a071286e85acc29ff48cfec3dfc93f944f00fce71e1d79fb44cff47ad' 
  AND token = 'zc7lIZpFe716xXM9CSxDK1w7gzEKVXHZGjrHc/VgUag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}