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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10d36242975cb44c899ecc9ac9cf4c3c3bb26de1481e060afce373f440fbd45a' 
  AND token = 'O7wYABRuUfTNvRacx0uCPll0QAcgtdCpFS2Ril9NsyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}