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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e816e1d22168cd0c572cd15ce6a06c282aca2c34199c19ddd5a9c5c310dc484' 
  AND token = '/Th/i2dHsh0Iqb/3IcrBLvoMuTeKB2Mc641xa4mtUPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}