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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80ed57152425c40dc50c66e26ad290884561116b4a003c2c222f484f609719d' 
  AND token = 'sGksKIwM02myPyTA4Z9jmkly1XDto/liU5k/5XLRUAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}