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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372bbf35e6937a451d235a8ffac63700d62eb8eef7f53c519457463e45140de0' 
  AND token = 'xdNKKc9nvfJz+AshRlRlldK4rmvmo4XxV2vSErKBuK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}