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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0738f9c11b1f1921607c1e124e97d92a3959f85e5951c351dee5b8c47a52c02b' 
  AND token = 'yMyyVnnIKl9AW7kmN8JqKU5K2C6GBFB3Vj3w5w5uofw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}