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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c20f453245336be02f968092d128ca6192d791e48cfb3b6a4f068c7e7b60bc3' 
  AND token = 'EYDROMivPgFTfzv+516WQ0t+PsNBM8G7d8qpORaTbbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}