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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86143334d73ebd7558401673343d1da5323f3ef8dc60cb61ed5cd4034f2a6031' 
  AND token = 'zd9qNaNkzlGSRLo/yPfD9wVj+t8B/8DOCSP4YNcgYMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}