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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd2d5415f0e78fbdeecea9e8d3f5e8bebf0c4c5a7fda8a3217e18d422f4ee627' 
  AND token = 'zdORKsA4P//wl2jHKwuggRQKhkgGyz5DPXrQDq2ZkcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}