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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '510f452a0d25c309e52b02aabefab1d5dcba0f4ee49f1eddcd503be1a378c1f5' 
  AND token = 'gaZLNJg6WWO+ItBHrqbqlwK5TD/VKmKI7it4V8z/w7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}