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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0602b057d7efd3fda57cdbdbf82b9bf40c6edce0162b99d16d4dae24cb577962' 
  AND token = 'tphM0+BzA2/IeuITA5kAJ/KnG+bi2NjkLDKRmkVUYe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}