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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e404739a21be0071cad5f981322215a1ac3fde6a23429710b56c4b23f9e7e53' 
  AND token = 'yydZU5/AH6gKtiaV/9Db1whhDXVcNn5F6NDE2VY0KNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}