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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '910b0d052070b6750cd8d7dfa8dc1693592a0f31b0c305baa6887b9345ac6261' 
  AND token = 'IieLQe/qLP57+kUO+xalsUrHz/hTqFIJpAGiQLsKqag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}