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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372961e1255dfdf3a7ec24737ce356f249ba6d765e543612429922c6729f7fee' 
  AND token = 'mPliJdrvTn2++DSBUMuwQqAMvgk9HbI/8+R06kpfp20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}