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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f535c17c612d31c94c1eb12ba02fda0e4e3c24fb76b880b65c4fbddff743d7' 
  AND token = 'jn+d2OYLHM2H5rGPl03D3Tr7dowin+HfByqw6BteDsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}