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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04f3b063e5de43abb33bb6d9f329721f18f2a05b6aeaf16c8829c603f0107593' 
  AND token = 'C3KkwWvyNsVtwgB/EdwEX3w1b6ATX6hERvVVt8VTCsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}