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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c7cf42f84f6e81f0f44e55076bafbdda01f15bff2a92af57479592edff4336' 
  AND token = '1VHBwLBOnZtfjDx+0qgtoeUefHOp/soPLhdFHiuAvd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}