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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461d6dd02d35ae09a9885219dc6fa4ab28ea14ccbe9dddac4e0ce1ae440a1282' 
  AND token = 'S//Iu3BYHJpCVae39uu8JRQPUptmyRos+S/tcP8oBmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}