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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7530907fdd69132618889db93a8c2f97afb024c4bf4282db7b801fba6c269ccc' 
  AND token = 'RPNYLqaCT7tJaUTQdTGZvx0E/R5rXbHX+Ur7P+4A1SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}