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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '405b5f938ba20753931e529fb09dad78a3bf1f649f07561b5e338c279cf24550' 
  AND token = '3/e5AL1W9OzDCFzvSGNbbMpfMPmr/xypDsvSmgGnx7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}