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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7151a8d98bd017740aee9c63c92bb00b78fff19658ac5fd6a891aefe521cc0e2' 
  AND token = '0dextQE0Xa2dSzj6nx+B76iuqLA7ZD8inFh7QF1zNqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}