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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5376d188c11a2c78a4080274ddf91bf1114c796a894c0cedff6a86bc35f46ec3' 
  AND token = 'CFS8meNsKurBz5JOuZjdPvk+xOZNvv1IbkFZEblp1Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}