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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4990cd22f68d1455394d3fe0b7d8fed2111c6097e9d5ad10bd4c519c6ecf7599' 
  AND token = 'ruEd4bKNasaS0pN47GMVsIzX25YygZVnGp1GUi5jVD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}