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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '482418394a8c470554271a84f124d38fd8142bfa74181948de8053579fe70d31' 
  AND token = 'JK8O+kXN8UCwF0g7OWxX/6EhusEjeyUdrHvpWwlNijk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}