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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f07a674d936a773743f9a7828fac7cb75488bdbd3b6b1544bc731e16b36a295' 
  AND token = 'JJG0/yS92Kly72pi+o/ZxTzbZgGKkKfaccMc+9thGgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}