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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a6d5671bdc3a9e541255cb3166e340de08a46a515a97f9848660bcaa83819f' 
  AND token = 'xEBdfOF1fdd842GqemTodd8iZH15435a54OqXHJwSnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}