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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6588ea9b81c91ba3e671cb1a77854021d7d033fe8156b7fc6878b2494a003d50' 
  AND token = '4RaoBZxXvjwMBpwVA/nEFCJRD6Wnaf3xFh/TI10VRTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}