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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c9da878cdd7a18713320b9b9fa4e9a6e5724e22b168a5595264131a5b7a3d6a' 
  AND token = 'uRdTWuiyqK+Kxeyoat8grv0+Y5wX9FBlLBUiTu1/Mq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}