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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17d8dd9b04a422788461fdb289448e83623080ad35ae8f5556f656f2bbdca788' 
  AND token = '+gZy41DZ9ouzJMBfggaiSO3PfPlSg3SAl4IZliDF5oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}