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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1582393bbb7d02c7b051d2d54a549e7c4b8b670442fefae9ada84357f2d28f' 
  AND token = '8fViFDGBJDNsdpWD2PFwO484sW6P4eiRnXQzmF6/ujs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}