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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edfaa8109ea30d3ca2c0588e3a464ee6548fd082996f42f7eb6f6c1f69a062d2' 
  AND token = '8IMRFJOPOB6e4Ax4fOOv32waKqDpcT5gHvIHCuxkMCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}