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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12b657ada8ae08d56b4e76dedc26f263d574c86036d6a9b6a10387adb02276fd' 
  AND token = 'diiZVyH4W0Ncde8WRTqxzDMd0ioE81TRp4s0uH0pUSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}