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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489cc0b86856e0afa4ee1e6db85d64314a2f2eb807ae44996c5af00371f326d3' 
  AND token = 'IVmGOeR+pwO2nZfvCyG2JQmnwIMf1H3sAERJpbQgKn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}