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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c985a2e06c6f0f2a55fcaf3be341552ec257f7631150adc34425b5a5e1e3e823' 
  AND token = 'nBxqQbpwhvvCfh6O9KySWGt4bxz0VoxKhD+RA8CdYKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}