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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22abffc87f7a893e6787d13f1e91857676dc6dcb9282861b172083aef0bb4476' 
  AND token = '0yFnabSO9ewcSZOJx4MXdYC3mQcOrj0xcog+tRdCEDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}