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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f6d4060f1737fbad668ca52c8438f40861451b644962c6cfffab07e19ffa29d' 
  AND token = '0m8GV+967oEZdzJmlFFFHxb78CuhLfkWS5+Zu5Z/+nA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}