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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7af3eabbdcbf6f8c13243742abaa2398018a5e9d0fd594a5488d5ccd144a357e' 
  AND token = 'Z74z64QSEwWb/P3WbleTOjwsjbVeZ/sFB4oMNYtutRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}