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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e35fc18db8bccfcdc6fad6cf2743f67d16206c1edd1c9b3017d3a3dbe3a0227' 
  AND token = 'OEdD6mf3T0qRA+G0bJidxgU5tGtxlI9d5Ylhm9FbsS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}