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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9762f2e3f2e1cf8a32adff96ff4de5917e468c105d46a6fcdbdd59e4d64f9953' 
  AND token = 'NjTkiAFcXjLrR7fHndXVaUkfqhqcUXpnpSxo4oiV4dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}