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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ded4ea9f7644c58cde0ddbe409b9d555b2cf22777f40bce031845822c903c901' 
  AND token = 'Up4p30tbKFWffRJm8NTq8FwbDBWWra3b6W6mndErka4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}