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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0581c1fb5feb09fbe7fddf9ce49a2f684c603d0a942ae61687e8acb59d1cd069' 
  AND token = 'RWBGhAHuB1w3G7aF5j265DeDOM97fYTx+kbIlaW2b4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}